Abstract Hydrogels with interpenetrating polymer network (IPN) show distinct advantages including enhanced mechanical properties and multiple functions. In this work, we prepared a series of dendronized IPN hydrogels by cryogelation technique using reversible Schiff-base crosslinked oligoethylene glycol (OEG)-based dendronized polymers to form one network, and covalent crosslinked polyacrylamide (PAAm) to form another network. These cryogels not only exhibit high mechanical strength with interconnected porous morphology, but also inherit characteristic thermoresponsive property from OEG-based dendronized polymers, and show thermally induced deswelling behavior upon heating to above their phase transition temperatures. Thermally induced reversible dehydration/rehydration of the OEG-based dendronized polymers and pH-mediated reversible formation of dynamic Schiff-base linkages afford the IPN cryogels amazingly dual-shape memory capability. Effects of polymer composition and fabrication method (one-pot/two-steps) on porous structures, responsive behavior, as well as mechanical properties of these dendronized IPN cryogels were investigated in details. We believe present work provides a convenient strategy to fabricate novel smart hydrogels with unique thermoresponsive and adaptive features, which could act as promising scaffolds for bio- or actuator applications

中文翻译：

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来自树枝状互穿聚合物网络的热响应冷冻凝胶显示出双重形状记忆

摘要 具有互穿聚合物网络（IPN）的水凝胶显示出明显的优势，包括增强的机械性能和多种功能。在这项工作中，我们使用可逆席夫碱交联低聚乙二醇 (OEG) 基树枝化聚合物形成一个网络，并使用共价交联聚丙烯酰胺 (PAAm) 形成另一个网络，通过冷冻凝胶化技术制备了一系列树枝化 IPN 水凝胶。这些冷冻凝胶不仅表现出具有互连多孔形态的高机械强度，而且还继承了基于 OEG 的树枝状聚合物的特征热响应特性，并且在加热到其相变温度以上时表现出热诱导消溶胀行为。基于 OEG 的树枝状聚合物的热诱导可逆脱水/再水化和 pH 介导的动态席夫碱键的可逆形成为 IPN 冷冻凝胶提供了惊人的双重形状记忆能力。详细研究了聚合物组成和制备方法（一锅/两步）对这些树枝状 IPN 冷冻凝胶的多孔结构、响应行为以及机械性能的影响。我们相信目前的工作提供了一种方便的策略来制造具有独特的热响应和自适应特征的新型智能水凝胶，它可以作为生物或致动器应用的有前途的支架 详细研究了这些树枝状 IPN 冷冻凝胶的响应行为以及机械性能。我们相信目前的工作提供了一种方便的策略来制造具有独特的热响应和自适应特征的新型智能水凝胶，它可以作为生物或致动器应用的有前途的支架 详细研究了这些树枝状 IPN 冷冻凝胶的响应行为以及机械性能。我们相信目前的工作提供了一种方便的策略来制造具有独特的热响应和自适应特征的新型智能水凝胶，它可以作为生物或致动器应用的有前途的支架