Serum neurofilament light (NfL)-chain is a circulating marker for neuroaxonal injury and is also associated with severity of cerebral small vessel disease (SVD) cross-sectionally. Here we explored the association of serum-NfL with imaging and cognitive measures in SVD longitudinally.

中文翻译：

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血清神经丝轻链与进展性脑小血管疾病的事件腔隙有关。

血清神经丝轻链（NfL）是神经轴突损伤的循环标志物，并且横断面还与脑小血管疾病（SVD）的严重程度有关。在这里，我们探讨了血清NfL与SVD中的影像学和认知指标的关联。