Nanotechnologies have become one of the primary directions in the development of biosensing technologies. These nano-enhanced biosensors can achieve a lower limit of detection and better sensing characteristics than traditional sensors can. Within these biosensing technologies, impedimetric biosensors, which have been developed for decades in sensing technologies, have obtained great progress with the momentums of nanotechnologies. To address these advancements of nano-enhanced impedimetric biosensing technologies, in this work, we mainly focus on reviews of nanomaterial-based and nanostructure-based impedimetric biosensors. At the same time, several promising new assays based on nanotechnology are also summarized. And the relationship between the limit of detection to nanoscale techniques is presented to promote the following developments of nanoscale biosensing technologies.

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评述—阻抗式生物传感技术中的纳米结构和材料的进步

纳米技术已成为生物传感技术发展的主要方向之一。与传统传感器相比，这些纳米增强型生物传感器可以实现更低的检测极限和更好的传感特性。在这些生物传感技术中，已经在传感技术领域开发了数十年的阻抗式生物传感器随着纳米技术的发展而取得了长足的进步。为了解决纳米增强型阻抗式生物传感技术的这些进步，在本工作中，我们主要侧重于基于纳米材料和基于纳米结构的阻抗式生物传感器的综述。同时，还总结了几种基于纳米技术的新方法。