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oposSOM-Browser: an interactive tool to explore omics data landscapes in health science
BMC Bioinformatics ( IF 2.9 ) Pub Date : 2020-10-19 , DOI: 10.1186/s12859-020-03806-w
Henry Loeffler-Wirth 1 , Jasmin Reikowski 1 , Siras Hakobyan 2 , Jonas Wagner 3 , Hans Binder 1
Affiliation  

oposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization. These functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and gene set profiles, of molecular ‘portrait landscapes’, of associated phenotype diversity, and signalling pathway activation patterns. The oposSOM-Browser makes available interactive data browsing for five transcriptome data sets of cancer (melanomas, B-cell lymphomas, gliomas) and of peripheral blood (sepsis and healthy individuals) at www.izbi.uni-leipzig.de/opossom-browser .

中文翻译:


oposSOM-Browser:探索健康科学组学数据景观的交互式工具



oposSOM 是一款基于机器学习的综合性开源数据分析软件,结合了多样性分析、生物标志物选择、功能挖掘和可视化等功能。这些功能现在可作为交互式网络浏览器应用程序,供有兴趣从 oposSOM 预处理的高通量组学数据集中提取详细信息的更广泛的用户受众使用。它可以交互式浏览单基因和基因组图谱、分子“肖像景观”、相关表型多样性以及信号通路激活模式。 oposSOM-Browser 提供癌症(黑色素瘤、B 细胞淋巴瘤、神经胶质瘤)和外周血(脓毒症和健康个体)五个转录组数据集的交互式数据浏览,网址为 www.izbi.uni-leipzig.de/opossom-browser 。
更新日期:2020-10-19
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