Abstract

A simple, sensitive and high-throughput method has been developed for the determination of triethyl tin (TET), tributyl tin (TBT) and triphenyl tin (TPhT) in environmental water samples using dispersive liquid-liquid microextraction (DLLME) and ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS). The effects of several parameters, including the type and volume of extraction solvent, type and volume of disperser solvent, and influence of salt and extraction time, were investigated. Under the optimized conditions, 25.0 µL of chlorobenzene were used as the extractant solvent. The enrichment factors were 168, 187, 175 for triethyl tin, tributyl tin, and triphenyl tin, respectively. Good linear relationships for the three organotin compounds were obtained across the range from 0.05 to 5.0 µg/L, and the limits of detection were from 0.003 to 0.010 µg/L based on a signal-to-noise ratio of three. The method was successfully applied to the analysis of seawater, river water and lake water samples with spiked recoveries from 81.4 to 109%, with the relative standard deviations from 4.2 to 8.4% (n = 6) obtained.

摘要

建立了一种简单，灵敏，高通量的方法，采用分散液-液微萃取（DLLME）和超高效液相色谱法测定环境水样中的三乙基锡（TET），三丁基锡（TBT）和三苯基锡（TPhT）。液相色谱与串联质谱联用（UPLC-MS / MS）。研究了几种参数的影响，包括萃取溶剂的类型和体积，分散剂溶剂的类型和体积以及盐和萃取时间的影响。在最佳条件下，将25.0 µL氯苯用作萃取溶剂。三乙基锡，三丁基锡和三苯基锡的富集系数分别为168、187、175。三种有机锡化合物在0.05至5.0 µg / L的范围内均具有良好的线性关系，基于3的信噪比，检测限为0.003至0.010 µg / L。该方法成功地用于分析加标回收率为81.4％至109％的海水，河水和湖水样品，相对标准偏差为4.2％至8.4％（n = 6）。