Tissue-mimicking materials (TMMs) play a key role in the quality assurance of ultrasound diagnostic equipment and should have acoustic properties similar to human tissues. We propose a method to quantify the acoustic properties of TMM samples through the use of an 80 MHz Scanning Acoustic Microscopy (SAM), which provides micrometer resolution and fast data recording. We produced breast TMM samples in varying compositions that resulted in acoustic impedance values in the range of 1.373 ± 0.031 and 1.707 ± 0.036 MRayl. Additionally, liver TMM and blood mimicking fluid (BMF) samples were prepared that had acoustic impedance values of 1.693 ± 0.085 MRayl and 1.624 ± 0.006 MRayl, respectively. The characterization of the TMMs by SAM may provide reproducible and uniform acoustic reference data for tissue substitutes in a single-run microscopy experiment.

中文翻译：

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使用扫描声学显微镜测量组织模拟材料的声阻抗

组织模拟材料 (TMM) 在超声诊断设备的质量保证中起着关键作用，并且应具有类似于人体组织的声学特性。我们提出了一种通过使用 80 MHz 扫描声学显微镜 (SAM) 来量化 TMM 样品声学特性的方法，该方法提供微米分辨率和快速数据记录。我们生产了不同成分的乳房 TMM 样本，导致声阻抗值在 1.373 ± 0.031 和 1.707 ± 0.036 MRayl 的范围内。此外，制备的肝脏 TMM 和血液模拟液 (BMF) 样品的声阻抗值分别为 1.693 ± 0.085 MRayl 和 1.624 ± 0.006 MRayl。SAM 对 TMM 的表征可以为单次显微镜实验中的组织替代品提供可重复且统一的声学参考数据。