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The potential of electrochemistry for the detection of coronavirus-induced infections
Trends in Analytical Chemistry ( IF 11.8 ) Pub Date : 2020-10-17 , DOI: 10.1016/j.trac.2020.116081
Rachel Rui Xia Lim 1 , Alessandra Bonanni 1
Affiliation  

Human coronaviruses (HCoV) are no stranger to the global environment. The etiology of previous outbreaks with reported symptoms of respiratory tract infections was attributed to different coronavirus strains, with the latest global pandemic in 2019 also belonging to the coronavirus family. Timely detection, effective therapeutics and future prevention are stake key holders in the management of coronavirus-induced infections. Apart from the gold standard clinical diagnostics, electrochemical techniques have also demonstrated their great potentials in the detection of different viruses and their correlated antibodies and antigens, showing high sensitivities and selectivities, and faster times for the analysis. This article aims to critically review the multifaceted electrochemical approaches, not only in the development of point-of-care portable devices but also as alternative detection strategies that can be coupled with traditional methods for the detection of various strains of coronaviruses.



中文翻译:


电化学检测冠状病毒引起的感染的潜力



人类冠状病毒(HCoV)对于全球环境来说并不陌生。此前报告的呼吸道感染症状暴发的病因可归因于不同的冠状病毒株,2019年最新的全球大流行也属于冠状病毒家族。及时检测、有效治疗和未来预防是管理冠状病毒引起的感染的关键。除了临床诊断的黄金标准外,电化学技术还展示了其在检测不同病毒及其相关抗体和抗原方面的巨大潜力,表现出高灵敏度和选择性以及更快的分析时间。本文旨在批判性地回顾多方面的电化学方法,不仅用于即时便携式设备的开发,而且还作为可与检测各种冠状病毒毒株的传统方法相结合的替代检测策略。

更新日期:2020-10-30
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