Objective

To determine the relationship between psychosocial caregiver disorders and childhood asthma.

Study design

We performed a matched case–control study with asthmatic children (6-14 years of age) from two different clinics in Zaragoza, Spain, between 2010 - 2016. Clinical data were collected from medical records and psychosocial disorders were assessed by interviewing the caregiver using validated questionnaires (Goldberg, CES-D, SF-12, PSS and SPIN). General analysis of cases and controls was performed using McNemar, Chi² and Wilcoxon nonparametric tests. A logistic regression model to predict more severe asthma, adjusted by caregiver psychosocial disorders was performed.

Results

208 children were evaluated (104 cases). Mean age was 9.7 ± 2.4 years, with a male predominance (62.5%). Anxiety, social phobia, depression, acute and chronic psychological disorders, and poor quality of life related to mental health were significantly more prevalent in caregivers of asthmatic children (p<0.05). On multivariate analysis, all of the above disorders significantly increased the risk of uncontrolled asthma, where anxiety, acute psychological disorders, and chronic psychological disorders were the most significant (OR 8.54, 95%CI 3.46-21.05, p<0.001; OR 6.05, 95%CI 2.39-15.28, p<0.001; and OR 4.86, 95%CI 1.97-12.02, p=0.001, respectively).

Conclusion

The prevalence of psychosocial disorders in caregivers of asthmatic children is high, when compared to caregivers of healthy children. The presence of anxiety, social phobia, depression, and poor quality of life is associated with an increased risk of worse controlled asthma. Perhaps, early detection and treatment of these disorders could positively impact childhood asthma control.

中文翻译：

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小儿哮喘与护理人员心理状况的关系

目的

确定心理社会照料者疾病与儿童哮喘之间的关系。

学习规划

我们在2010年至2016年之间对来自西班牙萨拉戈萨的两个不同诊所的哮喘儿童（6-14岁）进行了匹配的病例对照研究。从医疗记录中收集临床数据，并通过与护理人员进行访谈来评估心理社会障碍，经过验证的问卷（Goldberg，CES-D，SF-12，PSS和SPIN）。使用McNemar，Chi ²和Wilcoxon非参数检验对病例和对照进行一般分析。进行了逻辑回归模型以预测更严重的哮喘，并通过照顾者的心理社会疾病进行了调整。

结果

对208名儿童进行了评估（104例）。平均年龄为9.7±2.4岁，男性占多数（62.5％）。哮喘儿童的照顾者中，焦虑症，社交恐惧症，抑郁症，急性和慢性心理疾病以及与心理健康相关的不良生活质量更为普遍（p <0.05）。在多因素分析中，上述所有疾病均显着增加了不受控制的哮喘风险，其中焦虑，急性心理疾病和慢性心理疾病最为严重（OR 8.54，95％CI 3.46-21.05，p <0.001； OR 6.05， 95％CI 2.39-15.28，p <0.001；或4.86，95％CI 1.97-12.02，p = 0.001）。

结论

与健康儿童的照料者相比，哮喘儿童的照料者的社会心理障碍患病率很高。焦虑，社交恐惧症，抑郁症和生活质量差的存在与控制哮喘恶化的风险增加相关。也许，早期发现和治疗这些疾病可能会对儿童哮喘的控制产生积极影响。