Living in natural environment, plants often suffer from various biotic and abiotic stresses. Phosphate deficiency is a common factor affecting crop production in field, while pathogen invasion is another serious problem. Here we report that Pi-deficient cotton plants exhibit enhanced resistance to Verticillium dahliae. Transcriptomic and histochemical analysis revealed that cotton phenylpropanoid pathway was activated under phosphate deficiency, including lignin and flavonoid biosynthesis. Metabolomic data showed that Pi-deficient cotton accumulates many flavonoids metabolites and displays obvious anti-fungi activity in terms of methanolic extract. Additionally, JA biosynthesis was activated under phosphate deficiency and the Pi-deficiency induced disease resistance was significantly attenuated in GhAOS knock down plants. Taken together, our study demonstrated that phosphate deficiency enhanced cotton resistance to V. dahliae through activating phenylpropanoid pathway and JA biosynthesis, providing new insights into how phosphate deficiency affects plant disease resistance.

中文翻译：

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缺磷通过激活茉莉酸生物合成和苯丙烷途径增强棉花对大丽轮枝菌的抗性

生活在自然环境中的植物经常受到各种生物和非生物胁迫的影响。缺磷是影响大田作物生产的常见因素，而病原体入侵是另一个严重的问题。在这里，我们报告说，缺磷的棉花植株对大丽轮枝菌的抗性增强。转录组学和组织化学分析表明，棉花苯丙烷途径在磷缺乏时被激活，包括木质素和黄酮类生物合成。代谢组学数据表明，缺磷棉花在甲醇提取物中积累了许多黄酮类代谢物，并显示出明显的抗真菌活性。此外，在缺乏磷酸盐的情况下，JA 生物合成被激活，并且在 GhAOS 敲除植物中，缺磷诱导的抗病性显着减弱。综合起来，