Abstract

New N-substituted enamino ketones were synthesized by directed transformation of 3-acetyl- and 3-benzoyl-5,6,7,8-tetrafluoro-4H-chromen-4-ones by the action of highly basic primary amines as a result of opening of the pyranone ring and deacylation. The synthesizedN-hexyl and N-octyl derivatives were evaluated for fungistatic and bacteriostatic activities.

中文翻译：

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基于3-Acyl-4 H -polyfluorochromen-4-ones的N-烷基烯氨基酮的合成及其抗菌活性

摘要

结果，在高碱性伯胺的作用下，通过直接转化3-乙酰基和3-苯甲酰基-5,6,7,8-四氟-4 H-铬烯-4-酮合成了新的N-取代的烯氨基酮。吡喃酮环的打开和脱酰作用。评价了合成的N-己基和N-辛基衍生物的抑菌和抑菌活性。