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Chemical Transformations of 4-(4-Aminophenyl)-2,6-diphenylpyrimidine
Russian Journal of Organic Chemistry ( IF 0.8 ) Pub Date : 2020-10-19 , DOI: 10.1134/s1070428020090146
A. A. Harutyunyan , S. G. Israyelyan , H. A. Panosyan , M. S. Safaryan , S. V. Dilanyan

Abstract

4-(4-Aminophenyl)-2,6-diphenylpyrimidine was synthesized by reaction of (E)-1-(4-aminophenyl)-3-phenylprop-2-en-1-one with benzamidine and was involved in a number of transformations at the amino group, which afforded N-(2,4-dinitrophenyl) and N-acyl derivatives, N-[4-(2,6-diphenylpyrimidin-4-yl)phenyl]-6-methyl-2-(methylsulfanyl)pyrimidin-4-amine, and substituted quinazolines containing a 2,4,6-triphenylpyrimidine fragment on N3. The reaction of 2-methylquinazolines with aromatic aldehydes gave substituted (E)-3-[(4-(2,6-diphenylpyrimidin-4-yl)phenyl]-2-styrylquinazolin-4(3H)-ones.



中文翻译:

4-(4-氨基苯基)-2,6-二苯基嘧啶的化学转化

摘要

4-(4-氨基苯基)-2,6-二苯基嘧啶是通过(E)-1-(4-氨基苯基)-3-苯基丙-2-烯-1-酮与苄am的反应合成的氨基上的N-(2,4-二硝基苯基)和N-酰基衍生物的N- [4-(2,6-二苯基嘧啶-4-基)苯基] -6-甲基-2-(甲基硫烷基) )嘧啶-4-胺,以及在N 3上包含2,4,6-三苯基嘧啶片段的取代喹唑啉。2-甲基喹唑啉与芳族醛的反应得到取代的(E)-3-[(4-(2,6-二苯基嘧啶-4-基)苯基] -2-苯乙烯基喹唑啉-4(3 H)-。

更新日期:2020-10-19
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