Iron‐Catalyzed and Air‐Mediated C(sp3)−H Phosphorylation of 1,3‐Dicarbonyl Compounds Involving C−C Bond Cleavage,Advanced Synthesis & Catalysis

当前位置： X-MOL 学术 › Adv. Synth. Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Iron‐Catalyzed and Air‐Mediated C(sp3)−H Phosphorylation of 1,3‐Dicarbonyl Compounds Involving C−C Bond Cleavage
Advanced Synthesis & Catalysis ( IF 4.4 ) Pub Date : 2020-10-15 , DOI: 10.1002/adsc.202001020
Yingcong Ou ₁ , Yuanting Huang ₁ , Yu Liu ₁ , Yanping Huo ₁ , Yang Gao ₁ , Xianwei Li ₁ , Qian Chen _{1,

2}

Affiliation

A C(sp³)−H phosphorylation has been achieved via the iron‐catalyzed cross‐coupling reactions between 1,3‐dicarbonyl compounds and P(O)−H compounds involving C−C bond cleavages with air as the oxidant. This transformation provides a straightforward way to construct C(sp³)−P bonds, leading to the formation of β‐ketophosphine oxides in up to 93% yield with good functional group tolerance.

中文翻译：

铁催化和空气介导的涉及C-C键断裂的1,3-二羰基化合物的C（sp3）-H磷酸化

AC（sp ³）-H磷酸化是通过1,3-二羰基化合物与P（O）-H化合物之间的铁催化交叉偶联反应实现的，其中C-C键的裂解以空气为氧化剂。这种转变为构建C（sp ³）-P键提供了一种直接的方法，导致以高达93％的产率形成β-酮膦氧化物，并具有良好的官能团耐受性。

更新日期：2020-12-22

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11