Anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is associated with IRF7, BANK1 and TBX21 polymorphisms in two populations,European Journal of Neurology

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Anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is associated with IRF7, BANK1 and TBX21 polymorphisms in two populations
European Journal of Neurology ( IF 4.5 ) Pub Date : 2020-10-16 , DOI: 10.1111/ene.14596
Y Shu _{1,

2} , J Guo ₃ , X Ma ₁ , Y Yan ₄ , Y Wang ₁ , C Chen ₁ , X Sun ₁ , H Wang ₅ , J Yin ₂ , Y Long ₆ , X Yan ₃ , Z Lu ₁ , F Petersen ₂ , X Yu ₂ , W Qiu ₁

Affiliation

Autoantibodies targeting the GluN1(NR1) subunit of the anti‐N‐methyl‐D‐aspartate receptor (NMDAR) cause encephalitis. Although it has been shown that anti‐NMDAR encephalitis is associated with human leukocyte antigen (HLA) loci, susceptibility genes for the disease outside the HLA loci remain unidentified. In this study, we aimed to explore the association of anti‐NMDAR encephalitis with non‐HLA genes.

中文翻译：

抗 N-甲基-D-天冬氨酸受体 (NMDAR) 脑炎与两个人群的 IRF7、BANK1 和 TBX21 多态性相关

靶向抗N-甲基-D-天冬氨酸受体 (NMDAR)的 GluN1(NR1) 亚基的自身抗体会导致脑炎。尽管已经证明抗 NMDAR 脑炎与人类白细胞抗原 (HLA) 基因座有关，但 HLA 基因座以外的疾病易感基因仍未确定。在本研究中，我们旨在探讨抗 NMDAR 脑炎与非 HLA 基因的关系。

更新日期：2020-10-16

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