Diabetic autonomic neuropathy affects the entire autonomic nervous system and can lead to dysfunction of the cardiovascular, gastrointestinal, and genitourinary organ systems. Genitourinary dysfunction associated with diabetic autonomic neuropathy includes diabetic bladder dysfunction, sexual dysfunction, and recurrent urinary tract infections. Urological complications in diabetes mellitus are very common; in fact, genitourinary complications are more common than diabetic neuropathy or nephropathy. While several studies have reported on genitourinary dysfunction in individuals with diabetes, UroEDIC, an ancillary study to the Diabetes Control and Complications Trial (DCCT) and its observational follow up, the Epidemiology of Diabetes Interventions and Complications study (EDIC), comprehensively characterized the association between urologic complications and cardiovascular autonomic neuropathy. UroEDIC demonstrated significant associations between autonomic neuropathy and urologic complications in type 1 diabetes, specifically erectile dysfunction, female sexual dysfunction, and lower urinary tract symptoms. In this narrative review, we review the current literature on urological complications in diabetes.

中文翻译：

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糖尿病的自主神经病变和泌尿系统并发症

糖尿病自主神经病变影响整个自主神经系统，可导致心血管、胃肠道和泌尿生殖器官系统功能障碍。与糖尿病自主神经病变相关的泌尿生殖功能障碍包括糖尿病性膀胱功能障碍、性功能障碍和复发性尿路感染。糖尿病的泌尿系统并发症很常见；事实上，泌尿生殖系统并发症比糖尿病性神经病变或肾病更常见。虽然一些研究报告了糖​​尿病患者的泌尿生殖功能障碍，但 UroEDIC 是糖尿病控制和并发症试验 (DCCT) 的一项辅助研究及其观察性随访，即糖尿病干预和并发症流行病学研究 (EDIC)，综合描述了泌尿系统并发症与心血管自主神经病变之间的关系。UroEDIC 证明了 1 型糖尿病的自主神经病变和泌尿系统并发症之间存在显着关联，特别是勃起功能障碍、女性性功能障碍和下尿路症状。在这篇叙述性综述中，我们回顾了当前关于糖尿病泌尿系统并发症的文献。