Vaccine ( IF 5.5 ) Pub Date : 2020-10-16 , DOI: 10.1016/j.vaccine.2020.09.042 Marc Gurwith 1 , Richard C Condit 2 , Jean-Louis Excler 3 , James S Robertson 4 , Denny Kim 5 , Patricia E Fast 6 , Stephen Drew 7 , David Wood 4 , Bettina Klug 8 , Mike Whelan 9 , Tamala Mallett Moore 10 , Najwa Khuri-Bulos 11 , Emily R Smith 1 , Robert T Chen 1 , Sonali Kochhar 12 ,
Several live-attenuated viral vaccine candidates are among the COVID-19 vaccines in development. The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) has prepared a standardized template to describe the key considerations for the benefit-risk assessment of live-attenuated viral vaccines. This will help key stakeholders assess potential safety issues and understand the benefit-risk of such vaccines. The standardized and structured assessment provided by the template would also help to contribute to improved communication and support public acceptance of licensed live-attenuated viral vaccines.
中文翻译:
布莱顿协作病毒载体疫苗安全工作组 (V3SWG) 标准化模板,用于收集减毒活病毒疫苗的利益风险评估的关键信息
正在开发的 COVID-19 疫苗中有几种候选减毒活病毒疫苗。布莱顿协作病毒载体疫苗安全工作组 (V3SWG) 准备了一个标准化模板来描述减毒活病毒疫苗的利益风险评估的关键考虑因素。这将有助于主要利益相关者评估潜在的安全问题并了解此类疫苗的利益风险。模板提供的标准化和结构化评估也将有助于改善沟通并支持公众接受获得许可的减毒活病毒疫苗。