Newcastle disease (ND) is one of the most serious infectious and contagious viral diseases in avian species. Recently, several ND outbreaks in pigeon caused by pigeon paramyxovirus serotype-1 (PPMV-1) have been reported from Iran, but unfortunately, phylogenetic studies have been mostly conducted on partial sequence of NDV fusion (F) gene. In addition, a complete genome data of Iranian PPMV-1 strains are not available. In the present study, a PPMV-1, named Avian avulavirus 1/pigeon/Iran/UT-EGV/2018, isolated from an infected pigeon, was subjected to whole-genome sequencing. The isolate showed an MDT of 74 h, thus categorizing it as mesogenic. The phylogenetic analysis based on the F gene sequence revealed the isolate belongs to XXI.1.1 subgenotype (min 0.9 % and max 3 %). To our knowledge, our study is the first study to publish the complete genome of a PPMV-1 from Iran. According to BLAST results, the whole genome of UT-EGV had high homology with some Russian, Egyptian and Ukrainian strains (the highest was 96.55 %). Additionally, we conducted a phylogenetic analysis on five PPMV-1 that we isolated in 2014 to find that they may belong to a completely unreported subgenotype (6 % distance when compared as a group). The information obtained from this study can be useful in preventive measures, including constructing an effective vaccine against PPMV-1 in Iran.

新城疫（ND）是禽类中最严重的传染性和传染性病毒疾病之一。最近，伊朗报道了几只由副粘病毒血清型1（PPMV-1）引起的鸽子ND暴发，但不幸的是，系统发育研究主要是对NDV融合（F）基因的部分序列进行的。此外，还没有伊朗PPMV-1菌株的完整基因组数据。在本研究中，对从受感染的鸽子中分离出来的PPMV-1（称为禽短病毒1 /鸽子/伊朗/ UT-EGV / 2018）进行了全基因组测序。该分离物显示74 h的MDT，因此将其分类为介晶的。基于F基因序列的系统发育分析表明，该分离物属于XXI.1.1亚基因型（最小0.9％，最大3％）。据我们所知，我们的研究是第一个发表来自伊朗的PPMV-1完整基因组的研究。根据BLAST结果，UT-EGV的全基因组与一些俄罗斯，埃及和乌克兰菌株具有高度同源性（最高为96.55％）。此外，我们对2014年分离出的5种PPMV-1进行了系统发育分析，发现它们可能属于完全未报告的亚基因型（与一组相比，距离为6％）。从这项研究中获得的信息可用于预防措施，包括在伊朗构建针对PPMV-1的有效疫苗。我们对2014年分离出的5种PPMV-1进行了系统发育分析，发现它们可能属于完全未报告的亚基因型（与一组相比，距离为6％）。从这项研究中获得的信息可用于预防措施，包括在伊朗构建针对PPMV-1的有效疫苗。我们对2014年分离出的5种PPMV-1进行了系统发育分析，发现它们可能属于完全未报告的亚基因型（与一组相比，距离为6％）。从这项研究中获得的信息可用于预防措施，包括在伊朗构建针对PPMV-1的有效疫苗。