This work presents the preparation of an efficient and sensitive glucose sensor for the detection of glucose in an alkaline media. The glucose sensor is composed of a metal organic framework (MOF) composite comprising Ag@TiO₂ nanoparticles. The hybrid of Ag@TiO₂ encapsulated in ZIF-67 was synthesized by the solvothermal method and applied onto a glassy carbon electrode (GCE) for the non-enzymatic sensing of glucose. The porosity of ZIF-67 was favorable for the unhindered diffusion and entrapment of glucose and its cavities served as reaction vessels. The electrochemical behavior of Ag@TiO₂@ZIF-67 showed amplified results when compared with that of Ag@TiO₂ and ZIF-67. Cyclic tests toward the oxidation of glucose has demonstrated excellent stability of a MOF-based hybrid sensor. The sensor based on Ag@TiO₂@ZIF-67 showed high sensitivity of 0.788 μAμM⁻¹cm⁻² with a linear concentration range of 48 μM⁻¹ mM and a response time of 5 s with an excellent detection limit of 0.99 μM (S/N = 3).

这项工作提出了一种高效，灵敏的葡萄糖传感器的制备，用于检测碱性介质中的葡萄糖。葡萄糖传感器由包含Ag @ TiO ₂纳米粒子的金属有机骨架（MOF）复合材料组成。通过溶剂热法合成了包裹在ZIF-67中的Ag @ TiO ₂杂化物，并将其应用于玻璃碳电极（GCE）上，用于非酶感测葡萄糖。ZIF-67的孔隙度有利于葡萄糖的无阻扩散和截留，其空腔可作为反应容器。的Ag的TiO @的电化学行为₂当与银的@的TiO相比@ ZIF-67显示结果扩增₂和ZIF-67。对葡萄糖氧化的循环测试表明，基于MOF的混合传感器具有出色的稳定性。基于Ag @ TiO ₂ @ ZIF-67的传感器显示出0.788μAμM ^-1 cm ^-2的高灵敏度，线性浓度范围为48μM ^{- 1} mM，响应时间为5 s，检测极限为0.99μM（ S / N = 3）。