Objective: To assess incidence of urinary tract infection (UTI) among patients with recent spinal cord injury (SCI) who initiated intermittent catheterization (IC).

Design: Retrospective chart review.

Setting: Two European SCI rehabilitation centers.

Participants: Seventy-three consecutive patients with recent SCI who initiated IC.

Outcome measures: Incidence of UTI, using six different definitions, each based on microbiology ± symptomatology ± mention of UTI . Rates were expressed in terms of numbers of UTIs per 100 patient-months (PMs). Attention was focused on first-noted UTI during the three-month follow-up, as assessed with each of the six definitions.

Results: Fifty-eight percent of patients (n = 33) met ≥1 definitions for UTI during follow-up (rate: 31.5 UTIs per 100 PMs), ranging from 14% (5.3 per 100 PMs; definition requiring bacteriuria, pyuria, and presence of symptoms) to 45% (22.7 per 100 PMs; definition requiring “mention of UTI”). Ten cases were identified using the definition that required bacteriuria, pyuria, and symptoms, whereas definitions that required bacteriuria and either pyuria or symptoms resulted in the identification of 20–25 cases. Median time to UTI ranged from 42 days (“mention of UTI”) to 81 days (definition requiring bacteriuria and ≥100 leukocytes/mm³).

Conclusion: Depending on definition, 14% to 45% of patients with recent SCI experience UTI within three months of initiating IC. Definitions requiring bacteriuria and either pyuria or symptoms consistently identified about twice as many cases as those that required all three conditions. Standardizing definitions may help improve detection, treatment, and prevention of UTI within this vulnerable population.

目的：评估近期脊髓损伤（SCI）且开始间歇性导尿（IC）的患者尿路感染（UTI）的发生率。

设计：回顾性图表审查。

地点：两个欧洲 SCI 康复中心。

参与者：连续 73 名近期发生 SCI 并开始 IC 治疗的患者。

结果测量：尿路感染的发生率，使用六种不同的定义，每个定义基于微生物学±症状学±尿路感染的提及。比率以每 100 个患者月 (PM) 的尿路感染数量表示。在三个月的随访期间，注意力集中在首先注意到的尿路感染上，并根据六种定义中的每一种进行评估。

结果： 58% 的患者 ( n = 33) 在随访期间满足 ≥ 1 个 UTI 定义（比率：每 100 次下午 31.5 次尿路感染），范围为 14%（每 100 次下午 5.3 次；定义需要菌尿、脓尿和出现症状）至 45%（每 100 次下午 22.7 次；定义要求“提及尿路感染”）。使用需要菌尿、脓尿和症状的定义确定了 10 例病例，而需要菌尿和脓尿或症状的定义则确定了 20-25 例病例。发生尿路感染的中位时间范围为 42 天（“提及尿路感染”）至 81 天（定义需要菌尿且白细胞≥100 个/mm ³ ）。

结论：根据定义，近期 SCI 患者中有 14% 至 45% 在开始 IC 后三个月内经历过 UTI。需要菌尿和脓尿或症状的定义一致确定的病例数量大约是需要所有三种条件的病例的两倍。标准化定义可能有助于改善这一弱势群体中尿路感染的检测、治疗和预防。