ABSTRACT

Objective

This study assessed the consequences of childhood traumatic brain injury (TBI) on sleep, fatigue, depression, and quality of life (QoL) outcomes and explored the relationships between these variables at 20 years following childhood TBI.

Participants

We followed up 54 young adults with mild, moderate, and severe TBI, and 13 typically developing control (TDC) participants, recruited at the time of TBI.

Methods

Sleep was assessed with the Pittsburgh Sleep Quality Index and actigraphy.

Results

At 20 years postinjury, results showed no significant difference between whole TBI group and TDC participants on subjective sleep quality; however, the moderate TBI group reported significantly poorer subjective sleep quality compared to those with severe TBI. Poorer subjective sleep was associated with increased symptoms of fatigue, depression, and poorer perceptions of General Health in the TBI group. Actigraphic sleep efficiency, fatigue, depression, and QoL outcomes were not significantly different between TBI and TDC or among TBI severity groups.

Conclusions

These preliminary findings underscore associations between subjective sleep disturbance, fatigue, depression, and QoL in this TBI sample, and mostly comparable outcomes in sleep, fatigue, depression, and QoL between the TBI and TDC groups. Further research is required to clarify these findings.

中文翻译：

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患有儿童颅脑损伤的年轻成年人的睡眠障碍：与疲劳，抑郁和生活质量的关系

摘要

目的

这项研究评估了儿童创伤性脑损伤（TBI）对睡眠，疲劳，抑郁和生活质量（QoL）结果的后果，并探讨了儿童TBI发生20年后这些变量之间的关系。

参加者

我们追踪了54名患有轻度，中度和重度TBI的年轻人，以及在TBI时招募的13名典型的发展中对照（TDC）参与者。

方法

用匹兹堡睡眠质量指数和书法来评估睡眠。

结果

伤后20年，结果显示整个TBI组与TDC参与者在主观睡眠质量上没有显着差异；但是，中度TBI组的主观睡眠质量明显低于重度TBI。TBI组的主观睡眠不良与疲劳，抑郁和对一般健康的较差症状相关。TBI和TDC之间或TBI严重程度组之间的活动性睡眠效率，疲劳，抑郁和QoL结果无显着差异。

结论

这些初步发现强调了该TBI样本中的主观睡眠障碍，疲劳，抑郁和QoL之间的关联，以及TBI和TDC组之间在睡眠，疲劳，抑郁和QoL方面的可比较结果。需要进一步研究以澄清这些发现。