The National Institute of General Medical Sciences (NIGMS) at the U.S. National Institutes of Health (NIH) is committed to supporting the safety of the nation’s biomedical research and training environments. Institutional training grants affect many trainees and can have a broad influence across their parent institutions, making them good starting points for our initial efforts to promote the development and maintenance of robust cultures of safety at U.S. academic institutions. In this Perspective, we focus on laboratory safety, although many of the strategies we describe for improving laboratory safety are also applicable to other forms of safety including the prevention of harassment, intimidation, and discrimination. We frame the problem of laboratory safety using a number of recent examples of tragic accidents, highlight some of the lessons that have been learned from these and other events, discuss what NIGMS is doing to address problems related to laboratory safety, and outline steps that institutions can take to improve their safety cultures.

美国国立卫生研究院（NIH）的国立普通医学科学研究所（NIGMS）致力于支持该国生物医学研究和培训环境的安全性。机构培训补助金影响到许多受训人员，并且可以在其上级机构中产生广泛的影响，使它们成为我们为促进美国学术机构中健全的安全文化的发展和维护而做出的初步努力的良好起点。在此观点中，尽管我们描述的用于改善实验室安全性的许多策略也适用于其他形式的安全性，包括防止骚扰，恐吓和歧视，但我们仍将重点放在实验室安全性上。我们以最近发生的悲剧性事故为例，阐述了实验室安全的问题，