In this work, a novel and high-throughput parallel-dispersive droplet extraction (Pa-DDE) based on in situ formation of the hydrophobic MILs ([Co(C₄IM)₄⁺²]2[NTf₂^-], [Ni(C₄IM)₄⁺²]2[NTf₂^-] and [Ni(BeIM)₄⁺²]2[NTf₂^-]) is demonstrated, for the first time, for the determination of benzophenone, metolachlor, triclocarban, pendimethalin, 4-methylbenzylidene camphor, and 2-ethylhexyl-4-methoxycinnamate from aqueous environmental samples. This experimental setup is comprised of a 96-well plate system containing a set of magnetic pins which were used to collect the MIL droplet after in situ formation. This consolidated system enabled simultaneous extraction of up to 96 samples and MIL production in one step. Using this apparatus, sample preparation times of 0.78 min per sample was achieved. The experimental conditions were carefully optimized using uni and multivariate approaches. The optimal conditions were comprised of sample volume of 1.25 mL, 4 mg of [Co(C₄IM)₄⁺²]2[Cl⁻] and 40 μL of LiNTf₂ for the in situ formation, and dilution in 20 μL of acetonitrile. The analytical parameters of merit were successfully determined with LODs ranging from 7.5 to 25 μg L⁻¹ and coefficients of determination higher than 0.989. Intraday and interday precision ranged from 6.4 to 20.6% (n = 3) and 11.6–22.9% (n = 9), respectively, with analyte relative recovery ranging between 53.9 and 129.1%.

在这项工作中，基于疏水性MILs [[Co（C ₄ IM）₄ ⁺² ] 2 [NTf ₂ ^- ]，[Ni]的原位形成的新型高通量平行分散液滴提取（Pa-DDE）（C ₄ IM）₄ ² ] 2 [NTF ₂ ^- ]和[镍（BEIM）₄ ² ] 2 [NTF ₂ ^-]）首次证明可用于从水性环境样品中测定二苯甲酮，异丙甲草胺，三氯卡班，戊二甲灵，4-甲基亚苄基樟脑和2-乙基己基-4-甲氧基肉桂酸酯。该实验装置由96孔板系统组成，该系统包含一组磁性销，这些磁性销用于在原位形成后收集MIL液滴。这一整合的系统使一步可以同时提取多达96个样品和MIL产品。使用该设备，每个样品的样品制备时间达到0.78分钟。实验条件是使用单变量和多变量方法精心优化的。最佳条件包括1.25 mL样品体积，4 mg [Co（C ₄ IM）₄ ⁺²] 2 [氯^- ]和40μLLiNTf的₂的原位形成，并稀释在乙腈中的20μL。用7.5至25μgL ^-1的LOD成功测定了优异的分析参数，测定系数高于0.989。日内和日间精度分别为6.4％至20.6％（n = 3）和11.6-22.9％（n = 9），分析物相对回收率介于53.9％至129.1％之间。