Photobiomodulation is a brain modulation technique that has become a promising treatment for multiple pathologies. This systematic review collects studies up to 2019 about the beneficial effects of photobiomodulation as a therapy for treating psychological disorders and a tool for modulating cognitive processes. This technique is mostly used for the treatment of depression and stress, as well as to study its effects on psychological variables in healthy subjects. Despite the lack of parameters used, photobiomodulation seems to achieve enough brain penetration to produce beneficial effects in healthy subjects and patients with multiple pathologies. The best parameters are the wavelengths of 810 nm for the treatment of depression and 1064 nm for cognitive enhancement, along with a scalp irradiance of 250 mW/cm² and a scalp yield of 60 J/cm². It weekly application on the bilateral prefrontal area and the default mode network seems to be ideal for the maintenance of the effects. Photobiomodulation could be used as an effective and safe therapy for the treatment of multiple psychological pathologies.

光生物调节是一种脑调节技术，已成为多种疾病的有前途的治疗方法。这项系统的综述收集了直至2019年的有关光生物调节作为治疗心理疾病的疗法和调节认知过程的工具的有益作用的研究。该技术主要用于治疗抑郁症和压力，以及研究其对健康受试者心理变量的影响。尽管缺乏使用的参数，但光生物调节似乎可以实现足够的大脑渗透，从而在健康受试者和多种病理情况的患者中产生有益的作用。最佳参数是用于治疗抑郁的810 nm波长和用于认知增强的1064 nm波长，以及头皮辐照度250 mW / cm ²头皮产率为60J / cm ²。每周在双边前额叶区域和默认模式网络上进行应用似乎是维持效果的理想选择。光生物调节可以用作治疗多种心理疾病的有效且安全的疗法。