OBJECTIVE To determine whether body mass index (BMI) affects intrauterine insemination treatment success. DESIGN Retrospective cohort study. SETTING Academic medical center. PATIENT(S) A total of 3,217 intrauterine insemination treatment cycles in 1,306 patients. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Primary outcome was live birth rate stratified by BMI. Secondary outcomes included rates of clinical pregnancy (defined as an intrauterine pregnancy with a heartbeat present on ultrasound), multiple gestation, biochemical pregnancy, missed abortion, ectopic, and spontaneous abortion. RESULT(S) Women with BMI 25 to 29.99 kg/m2 or ≥30 kg/m2 were equally likely to have a live birth as women of normal BMI. Women with BMI ≥30 kg/m2 did have a higher likelihood of biochemical pregnancy than women with normal BMI. CONCLUSION(S) A BMI between 25 and 29.99 kg/m2 or ≥30 kg/m2 does not appear to have a negative effect on live birth after intrauterine insemination. Obesity may be associated with a higher risk of biochemical pregnancy after intrauterine insemination.

中文翻译：

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体重指数对宫内人工授精周期成功的影响

目的 确定体重指数 (BMI) 是否影响宫内人工授精治疗的成功。设计 回顾性队列研究。设置学术医疗中心。PATIENT(S) 在 1,306 名患者中总共进行了 3,217 个宫内人工授精治疗周期。干预措施 无。主要结局指标 主要结局是按 BMI 分层的活产率。次要结局包括临床妊娠率（定义为超声显示有心跳的宫内妊娠）、多胎妊娠、生化妊娠、错过流产、异位流产和自然流产率。结果 BMI 为 25 至 29.99 kg/m2 或≥30 kg/m2 的女性与 BMI 正常的女性一样有可能活产。BMI ≥ 30 kg/m2 的女性生化妊娠的可能性确实高于 BMI 正常的女性。结论 (S) BMI 介于 25 和 29.99 kg/m2 之间或≥30 kg/m2 似乎不会对宫内人工授精后的活产产生负面影响。肥胖可能与宫腔内人工授精后生化妊娠的风险增加有关。