Leptospirosis has been investigated in several species of wild animals. The white-eared opossum (Didelphis albiventris) is a mammal common in the brazilian semi-arid, so, this study aimed to investigate its role in the occurrence of the leptospirosis in the region Northeast of Brazil. 12 animals were used, from which samples were collected for the attempt of isolation, molecular detection and serological examination. There was no microbial growth, nor were any anti-Leptospira sp. antibodies found in the serological samples. The PCR detected leptospiric DNA in the central nervous system (CNS) of five animals (41.7 %). The gene in one of the samples was sequenced and showed identity with Leptospira interrogans. The presence of Leptospira sp. in the CNS of Didelphis albiventris does not allow the characterization of the studied animals as reservoirs with potential for transmission of the pathogen in the region, however it represents a site that needs to be further investigated.

钩端螺旋体病已在几种野生动物中进行了研究。白耳负鼠（Didelphis albiventris）是巴西半干旱地区常见的哺乳动物，因此，本研究旨在研究其在巴西东北部地区钩端螺旋体病发生中的作用。使用了12只动物，从它们中收集样品以进行分离，分子检测和血清学检查。没有微生物生长，也没有任何抗钩端螺旋体。血清样品中发现抗体。PCR检测到五只动物（41.7％）在中枢神经系统（CNS）中的钩端螺旋体DNA。其中一个样品中的基因被测序并与钩端螺旋体相同。钩端螺旋体的存在sp。Didelphis albiventris的中枢神经系统中的特征不允许将被研究动物定性为可能在该区域传播病原体的水库，但是它代表了一个有待进一步研究的地方。