Biofuels from biomass have attracted great attention due to the increasingly serious environmental problems and the increasing demand for fossil fuels. Butanol is considered as a promising alternative biofuel because of its favorable properties, and it can be produced by IBE fermentation broths. Moreover, the high-purity isopropanol-ethanol (IE) mixture produced by IBE fermentation can be used as a gasoline additive. However, the IBE purification process is hindered by its low concentration and energy-intensive separation from IBE fermentation broths. In this work, a novel 6-column distillation process for IBE purification is proposed to reduce the total energy consumption (TEC) and capital cost. Furthermore, for achieving further energy savings, the double-effect distillation (DED) and heat pump assisted distillation (HPAD) technologies are used as the process intensification methods. These processes are compared in terms of energy, economic and environmental impact. The results indicate that the total annual cost (TAC), TEC and gas emissions of the IBE purification process can be reduced effectively by the three intensification processes, among them, the process intensification with HPAD (PI-HPAD) process is the best one, which can achieve 46.72%, 26.96% and 30.52% savings of TEC, TAC and CO₂ emission, respectively.

由于日益严重的环境问题和对化石燃料的需求增加，来自生物质的生物燃料引起了极大的关注。丁醇由于其良好的特性而被认为是一种有前途的替代生物燃料，可以通过IBE发酵液生产。此外，通过IBE发酵生产的高纯度异丙醇-乙醇（IE）混合物可以用作汽油添加剂。但是，IBE的纯化过程因其浓度低和从IBE发酵液中分离能量密集而受到阻碍。在这项工作中，提出了一种新颖的用于IBE纯化的六塔蒸馏工艺，以减少总能耗（TEC）和资本成本。此外，为了进一步节省能源，双效蒸馏（DED）和热泵辅助蒸馏（HPAD）技术被用作工艺强化方法。对这些过程进行了能源，经济和环境影响方面的比较。结果表明，通过三种强化工艺可以有效降低IBE净化工艺的总年度成本（TAC），TEC和气体排放，其中以HPAD（PI-HPAD）工艺强化是最好的一种，可以节省TEC，TAC和CO的46.72％，26.96％和30.52％_2个发射。