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Fibrous osteodystrophy in a dromedary camel
The Journal of Veterinary Diagnostic Investigation ( IF 1.2 ) Pub Date : 2020-10-14 , DOI: 10.1177/1040638720965252
Elizabeth S Hines 1 , Valentina B Stevenson 1 , Molly E Patton 1 , Hannah R Leventhal 1 , Noah Diaz-Portalatin 1 , Mitchell A Meyerhoeffer 1 , Linda A Dahlgren 1 , D Phillip Sponenberg 1
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A 6-y-old female dromedary camel (Camelus dromedarius L.) was presented for assessment of firm, bilateral swellings rostral and ventral to the eyes. Serum biochemistry revealed hyperglycemia (28.5 mmol/L), hypocalcemia (1.27 mmol/L), hyperphosphatemia (3.39 mmol/L), hypoproteinemia (total protein 50 g/L), and hypoalbuminemia (20 g/L). Based on the poor prognosis associated with the presumptive diagnosis of fibrous osteodystrophy, the camel was euthanized. Gross postmortem findings revealed expanded fibrous tissue replacing the maxilla and mandible, and bilaterally prominent parathyroid glands. Histology of the maxilla revealed proliferative loose fibrous tissue with widely scattered, regularly spaced, small spicules of mineralized bone. The parathyroid glands were prominent bilaterally; the internal and external parathyroid glands were composed of plump cells with abundant pale basophilic cytoplasm and open nuclei. The pathologic findings were consistent with the antemortem diagnosis of fibrous osteodystrophy. The camel’s diet, which was not specifically balanced for a camel, included grass hay, sweet feed, and alfalfa pellets. The camel’s caregivers reported feeding her treats of cookies. A feed analysis was not available. The biochemistry abnormalities and clinical and postmortem findings, along with a diet that was not balanced for a camel, are consistent with a diagnosis of nutritional secondary hyperparathyroidism.



中文翻译:

单峰骆驼的纤维性骨营养不良

一头6 岁的雌性单峰骆驼 ( Camelus dromedariusL.) 用于评估眼睛的头侧和腹侧牢固的双侧肿胀。血清生化显示高血糖(28.5 mmol/L)、低钙血症(1.27 mmol/L)、高磷血症(3.39 mmol/L)、低蛋白血症(总蛋白 50 g/L)和低白蛋白血症(20 g/L)。基于与纤维性骨营养不良的推定诊断相关的不良预后,骆驼被安乐死。尸检结果显示扩大的纤维组织取代了上颌骨和下颌骨,以及双侧突出的甲状旁腺。上颌骨的组织学显示增生的松散纤维组织,具有广泛分散的、规则间隔的、小的矿化骨骨针。双侧甲状旁腺突出;内、外甲状旁腺由丰满的细胞组成,细胞质丰富,呈淡嗜碱性,核开放。病理结果与纤维性骨营养不良的死前诊断一致。骆驼的饮食没有特别均衡,包括干草、甜饲料和苜蓿颗粒。骆驼的看护者报告说给她喂了饼干。饲料分析不可用。生化异常、临床和尸检结果,以及骆驼的饮食不均衡,都与营养性继发性甲状旁腺功能亢进症的诊断一致。和苜蓿颗粒。骆驼的看护者报告说给她喂了饼干。饲料分析不可用。生化异常、临床和尸检结果,以及骆驼的饮食不均衡,都与营养性继发性甲状旁腺功能亢进症的诊断一致。和苜蓿颗粒。骆驼的看护者报告说给她喂了饼干。饲料分析不可用。生化异常、临床和尸检结果,以及骆驼的饮食不均衡,都与营养性继发性甲状旁腺功能亢进症的诊断一致。

更新日期:2020-10-15
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