This report is a follow-up to our two prior publications that analyzed solubility behaviors and correlations of common solvents. The statistical results reported herein, on a large number of common solvent–antisolvent systems, are obtained with the same log/log linear regression methodology. From the analysis, we have identified strong solubility correlations in many Type 1 (same solvent/antisolvent, different ratio) and Type 2 (same ratio/antisolvent, different solvent) solvent–antisolvent system pairs. Many of these solvent mixtures are amenable to solubility predictions based on a simple extrapolation methodology. These findings empower scientists to compress and optimize solubility screening designs by eliminating measurements that are likely to produce redundant information.

中文翻译：

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普通溶剂-反溶剂体系的溶解度行为及其相关性

该报告是对我们之前的两个出版物的后续报告，该出版物分析了溶解度行为和常见溶剂的相关性。本文报告的统计结果是使用相同的log / log线性回归方法获得的，在许多常见的溶剂-反溶剂系统上。通过分析，我们确定了许多类型1（相同溶剂/反溶剂，不同比例）和类型2（相同比例/反溶剂，不同溶剂）溶剂-反溶剂体系对之间的强溶解度相关性。这些溶剂混合物中的许多混合物都可以根据简单的外推方法进行溶解度预测。这些发现使科学家能够通过消除可能产生冗余信息的测量值来压缩和优化溶解度筛选设计。