In PNAS (1), we report the full-field interferometric imaging of the dynamics of neuronal deformations during the action potential. The imaging methodology we describe provides a noninvasive approach to observation of the neural signaling and also allows scientists to verify their models with more degrees of freedom provided by the spatial distribution of the deformations, compared to previous single-point measurements. We also show that the mechanical model based on voltage-dependent membrane tension proposed by Zhang et al. (2) fits our observations.

中文翻译：

---

回复法雷尔：实验证据是模型假设的最终判断[生物科学]

在PNAS（1）中，我们报告了动作电位期间神经元变形动力学的全场干涉成像。与先前的单点测量相比，我们描述的成像方法为神经信号的观察提供了一种非侵入性方法，还使科学家能够通过变形的空间分布提供更大的自由度来验证他们的模型。我们还表明，基于张等人提出的基于电压的膜张力的力学模型。（2）符合我们的观察。