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A case of personalized and precision medicine: Pharmacometabolomic applications to rare cancer, microbiological investigation, and therapy
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-10-14 , DOI: 10.1002/rcm.8976
Simone Cristoni 1 , Luigi Rossi Bernardi 2 , Amir Mohammad Malvandi 2 , Martina Larini 1 , Ermanno Longhi 2 , Francesco Sortino 3 , Matteo Conti 4 , Nicola Pantano 5 , Giovanni Puccio 6
Affiliation  

Advances in metabolomics, together with consolidated genetic approaches, have opened the way for investigating the health of patients using a large number of molecules simultaneously, thus providing firm scientific evidence for personalized medicine and consequent interventions. Metabolomics is an ideal approach for investigating specific biochemical alterations occurring in rare clinical situations, such as those caused by rare associations between comorbidities and immunosuppression.

中文翻译:

个性化精准医疗案例:药物代谢组学在罕见癌症、微生物研究和治疗中的应用

代谢组学的进步以及整合的遗传方法为同时使用大量分子研究患者的健康开辟了道路,从而为个性化医疗和后续干预提供了坚实的科学依据。代谢组学是研究罕见临床情况下发生的特定生化变化的理想方法,例如由合并症和免疫抑制之间的罕见关联引起的变化。
更新日期:2020-11-27
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