Liposomes modified with bio-substances for cancer treatment,Biomaterials Science

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Liposomes modified with bio-substances for cancer treatment
Biomaterials Science ( IF 5.8 ) Pub Date : 2020-10-13 , DOI: 10.1039/d0bm01531h
Yanan Li _{1,

2,

3,

4,

5} , Hailin Cong _{1,

2,

3,

4,

5} , Song Wang _{1,

2,

3,

4,

5} , Bing Yu _{1,

2,

3,

4,

5} , Youqing Shen _{1,

2,

3,

4,

5}

Affiliation

In recent years, liposomes have been used in the field of biomedicine and have achieved many significant results. Because of the unique characteristics of liposomes, there are many materials that can be loaded in many types of liposome, such as biologically active substances. Liposomes are made of lipid bilayers, which are very similar to cell membranes. They have many biological and technical advantages and have even been used in clinical practice because of their unique structure. As liposomes have hydrophobic cavities and hydrophilic cavities, they can simultaneously load hydrophobic and hydrophilic drugs. This causes an increase in the drug loading efficiency and therapeutic capability. Different therapeutic effects are achieved by different methods such as placing the biological materials in the bilayer structure of the liposome or encapsulating them in the liposome. By these methods, bio-simulated liposomes can achieve considerable cancer treatment effects. Now liposomes have become an independent platform and play an important role in many facets. In this review, we focus on the use of liposomes composed of biomaterials for the treatment of cancer. These include liposomes that mimic mammalian cells, bacteria, and viruses.

中文翻译：

用生物物质修饰的脂质体可治疗癌症

近年来，脂质体已用于生物医学领域，并已取得许多重要成果。由于脂质体的独特特性，许多材料可以装载到许多类型的脂质体中，例如生物活性物质。脂质体由脂质双层制成，与细胞膜非常相似。它们具有许多生物学和技术优势，并且由于其独特的结构甚至已在临床实践中使用。由于脂质体具有疏水腔和亲水腔，因此它们可以同时加载疏水和亲水药物。这导致药物装载效率和治疗能力的增加。通过不同的方法可以实现不同的治疗效果，例如将生物材料置于脂质体的双层结构中或将其包裹在脂质体中。通过这些方法，生物模拟脂质体可以达到可观的癌症治疗效果。现在，脂质体已成为一个独立的平台，并在许多方面发挥重要作用。在这篇综述中，我们重点研究由生物材料组成的脂质体在癌症治疗中的应用。这些包括模仿哺乳动物细胞，细菌和病毒的脂质体。我们专注于使用由生物材料组成的脂质体来治疗癌症。这些包括模仿哺乳动物细胞，细菌和病毒的脂质体。我们专注于使用由生物材料组成的脂质体来治疗癌症。这些包括模仿哺乳动物细胞，细菌和病毒的脂质体。

更新日期：2020-11-03

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