We assessed 168 patients with multiple sclerosis (MS) by force platform to obtain the dual-task cost (DTC) of balance, that is, the change in postural sway from quiet standing to dual-task condition (Stroop test). After a median follow-up time of 3.5 years from this assessment, disability progression occurred in 45 (27%) patients. Disability progression was predicted by the adoption of a 'posture second' strategy, that is, values of DTC of balance exceeding those obtained from 62 healthy controls, even after controlling by demographic and clinical characteristics. The DTC of balance may potentially represent a novel and easy tool to predict MS progression.

中文翻译：

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“姿势第二”策略可预测多发性硬化症的残疾进展

我们通过力平台评估了 168 名多发性硬化症 (MS) 患者，以获得平衡的双任务成本 (DTC)，即从安静站立到双任务状态的姿势摇摆变化（Stroop 测试）。中位随访 3.5 年后，45 名 (27%) 患者出现残疾进展。通过采用“姿势第二”策略来预测残疾进展，即平衡 DTC 值超过从 62 名健康对照获得的值，即使在通过人口统计学和临床​​特征进行控制之后也是如此。平衡 DTC 可能代表一种预测 MS 进展的新颖且简单的工具。