Insects have close symbiotic relationships with several microbes, which extends the limited metabolic networks of most insects. Using symbiotic microorganisms for the biological control of pests and insect-borne diseases has become a promising direction. Blattella germanica (L.) (Blattaria: Blattidae) is a public health pest worldwide, which is difficult to control because of its strong reproductive ability, adaptability, and resistance to insecticides. In this paper, the diverse biological functions (nutrition, reproductive regulation, insecticide resistance, defense, and behavior) of symbionts were reviewed, and new biological control strategies on the basis of insect–symbiont interaction were proposed. We highlight new directions in B. germanica control, such as suppressing cockroach population using Wolbachia or paratransgenes, and combining fungal insecticides with synergistic agents to enhance insecticidal efficacy.

中文翻译：

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蟑螂控制的新见解：利用德国小Bl共生菌的功能多样性

昆虫与几种微生物有着密切的共生关系，从而扩展了大多数昆虫有限的代谢网络。利用共生微生物防治害虫和虫媒疾病已成为一个有前途的方向。德国小att（Blattella germanica（L.））（Blattaria：Blattidae）是一种全球性的公共卫生害虫，由于其强大的繁殖能力，适应性和对杀虫剂的抵抗力而难以控制。本文综述了共生体的多种生物学功能（营养，生殖调控，杀虫剂抗性，防御和行为），并提出了基于昆虫与共生体相互作用的新生物防治策略。我们突出德国双歧杆菌的新方向防治，例如使用沃尔巴氏菌或副转基因抑制蟑螂种群，以及将杀真菌剂与增效剂结合使用，以增强杀虫效力。