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Worldwide survey on key indicators for public cord blood banking technologies: By the World Marrow Donor Association Cord Blood Working Group
STEM CELLS Translational Medicine ( IF 5.4 ) Pub Date : 2020-10-13 , DOI: 10.1002/sctm.20-0246
Monique Jöris 1 , Katie Paulson 2 , Lesa Foley 2 , Merry Duffy 2 , Sergio Querol 3 , Susana Gomez 3 , Etienne Baudoux 4
Affiliation  

The Cord Blood Working Group of the World Marrow Donor Association created a survey for cord blood banks (CBBs) aimed to identify and understand the main technical procedures currently used by public CBBs worldwide regarding cord blood units (CBUs) available for unrelated hematopoietic stem cell transplantation. These technical procedures include CBU collection, (pre‐) processing, packaging, testing, storage, and transport. The survey was an online survey created with SurveyGizmo and was completed individually by each CBB at the end of 2017. The information is valuable to transplant centers, CBBs as well as the global industry of public cord blood banking. In general, we can conclude from this survey that the majority of CBBs are up to standard in terms of CBB technologies. Areas of improvement include accreditation, increase standardization in testing, and setting of total nucleated cells thresholds for acceptance of CBU for public use. Furthermore, there is a need for a consensus in the way CBBs operate in term of reservation and release to facilitate a more straightforward access to the therapy.

中文翻译:


关于公共脐带血库技术关键指标的全球调查:世界骨髓捐赠者协会脐带血工作组



世界骨髓捐赠者协会脐带血工作组对脐带血库 (CBB) 进行了一项调查,旨在确定和了解全球公共 CBB 目前使用的有关可用于无关造血干细胞移植的脐带血单位 (CBU) 的主要技术程序。这些技术程序包括 CBU 收集、(预)加工、包装、测试、储存和运输。该调查是由 SurveyGizmo 创建的在线调查,由每个 CBB 于 2017 年底单独完成。这些信息对于移植中心、CBB 以及全球公共脐带血库行业都很有价值。总体来说,从本次调查中我们可以看出,大部分CBB在CBB技术方面都达到了标准。需要改进的领域包括认证、提高测试标准化以及设置接受 CBU 供公众使用的总有核细胞阈值。此外,需要就 CBB 在保留和释放方面的运作方式达成共识,以促进更直接地获得治疗。
更新日期:2020-10-13
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