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Melamine contamination and associated health risks: Gut microbiota does make a difference
Biotechnology and Applied Biochemistry ( IF 3.2 ) Pub Date : 2020-10-12 , DOI: 10.1002/bab.2050 Meenakshi Rajpoot 1 , Rajasri Bhattacharya 2 , Sheenam Sharma 3 , Sumeet Gupta 3 , Varruchi Sharma 4 , Anil K Sharma 5
Biotechnology and Applied Biochemistry ( IF 3.2 ) Pub Date : 2020-10-12 , DOI: 10.1002/bab.2050 Meenakshi Rajpoot 1 , Rajasri Bhattacharya 2 , Sheenam Sharma 3 , Sumeet Gupta 3 , Varruchi Sharma 4 , Anil K Sharma 5
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Melamine is a nitrogenous organic compound containing high amounts of nitrogen, which is interpreted as high protein in various standard protein measuring tests, therefore added to foods to boost the protein content. Illegal addition of melamine has been in practice by food manufacturers, which leads to toxicity and stone formation in kidneys of individuals consuming melamine-contaminated milk products. A focused and thorough structured search of bibliographic databases for peer-reviewed researches reported in the literature was carried out with a focused attention on melamine contamination, associated health risks, and the role of gut microbiota. The overall outcomes of the research and review articles pertaining to searched keywords along with analysis of the interventions have been described employing a deductive qualitative content analysis approach. Current review focuses on the various health risks associated with consumption of melamine-contaminated foods and the need to develop better and effective methods for its testing. Moreover, the importance of gut microbiota in mediating toxicity due to melamine has also been discussed as there is a link between toxicity and activities of gut microbiota.
中文翻译：
三聚氰胺污染和相关的健康风险：肠道微生物群确实有所作为
三聚氰胺是一种含有大量氮的含氮有机化合物，在各种标准蛋白质测量测试中被解释为高蛋白质，因此添加到食物中以提高蛋白质含量。食品制造商在实践中非法添加三聚氰胺，这会导致食用受三聚氰胺污染的奶制品的人的肾脏出现毒性和结石形成。对文献中报道的同行评议研究的书目数据库进行了重点和彻底的结构化搜索，重点关注三聚氰胺污染、相关健康风险和肠道微生物群的作用。已采用演绎定性内容分析方法描述了与搜索关键字有关的研究和评论文章的总体结果以及对干预措施的分析。目前的审查侧重于与食用受三聚氰胺污染的食品相关的各种健康风险，以及开发更好、更有效的检测方法的必要性。此外，还讨论了肠道微生物群在介导三聚氰胺毒性方面的重要性，因为毒性与肠道微生物群的活性之间存在联系。
更新日期：2020-10-12
中文翻译：
三聚氰胺污染和相关的健康风险：肠道微生物群确实有所作为
三聚氰胺是一种含有大量氮的含氮有机化合物，在各种标准蛋白质测量测试中被解释为高蛋白质，因此添加到食物中以提高蛋白质含量。食品制造商在实践中非法添加三聚氰胺，这会导致食用受三聚氰胺污染的奶制品的人的肾脏出现毒性和结石形成。对文献中报道的同行评议研究的书目数据库进行了重点和彻底的结构化搜索，重点关注三聚氰胺污染、相关健康风险和肠道微生物群的作用。已采用演绎定性内容分析方法描述了与搜索关键字有关的研究和评论文章的总体结果以及对干预措施的分析。目前的审查侧重于与食用受三聚氰胺污染的食品相关的各种健康风险，以及开发更好、更有效的检测方法的必要性。此外，还讨论了肠道微生物群在介导三聚氰胺毒性方面的重要性，因为毒性与肠道微生物群的活性之间存在联系。
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