In this work, the modification of ethylene-co-vinyl alcohol (EVOH) copolymer with a coumarin derivative, 7-(hydroxyethoxy)-4-methyl coumarin (HEOMC), has been performed through the incorporation of different reactive groups, p-nitrophenyl chloroformate, succinic anhydride and phthalic anhydride as different linkers between coumarin and EVOH with the aim to obtain photo-responsive materials with improved protein absorption resistance. After purification, the modification degree was calculated by nuclear magnetic resonance and ultraviolet-visible spectroscopy. The thermal properties revealed the crystallinity loss and higher maximum degradation temperatures when EVOH is modified with coumarin derivative. Copolymers were successfully photo-crosslinked through the photo-responsive behavior of coumarin moieties. The micro-hardness test shown an increase of the mechanical performance due to the coumarin presence. The water contact angle measurements revealed that while coumarin-modified EVOH copolymers present a higher hydrophilic behavior than EVOH, the photo-dimerization process mainly leads to slightly deviations on the surface wettability of neat EVOH. Finally, the absorption of bovine serum albumin onto the surface of the coumarin-modified materials revealed enhanced antifouling properties, particularly after the photo-crosslinked process. Therefore, the introduction of coumarin through different chain extenders leads to functional materials with tunable photo-responsive performance and protein absorption resistance.

在这项工作中，已通过引入不同的反应性基团p对香豆素衍生物7-（羟基乙氧基）-4-甲基香豆素（HEOMC）进行了乙烯-共-乙烯醇（EVOH）共聚物的改性。-硝基苯甲酸氯甲酸酯，琥珀酸酐和邻苯二甲酸酐作为香豆素和EVOH之间的不同连接体，旨在获得具有提高的蛋白质吸收抗性的光敏材料。纯化后，通过核磁共振和紫外可见光谱法计算改性度。当用香豆素衍生物改性EVOH时，热性能显示出结晶度损失和最高最高降解温度。共聚物通过香豆素部分的光响应行为成功地进行了光交联。显微硬度测试表明由于香豆素的存在，机械性能有所提高。水接触角的测量表明，香豆素改性的EVOH共聚物的亲水性比EVOH高，光二聚过程主要导致纯净EVOH的表面润湿性略有偏差。最后，牛血清白蛋白在香豆素改性材料表面的吸收显示出增强的防污性能，尤其是在光交联过程之后。因此，通过不同的扩链剂引入香豆素会导致功能材料具有可调的光响应性能和抗蛋白质吸收能力。