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CD226 Throttles up CD8+ T Cell Antitumor Activity
Immunity ( IF 25.5 ) Pub Date : 2020-10-13 , DOI: 10.1016/j.immuni.2020.09.013
Mary Philip 1
Affiliation  

In this issue of Immunity, Weulersse et al. and Braun et al. explain how CD226 expression loss on CD8+ T cells impairs TCR-driven activation, and thereby anti-tumor effector responses, tantamount to taking the CD8+ T cell’s foot off the gas pedal.



中文翻译:

CD226 抑制 CD8+ T 细胞抗肿瘤活性

在本期Immunity中,Weulersse 等人。和布劳恩等人。解释 CD8 + T 细胞上的 CD226 表达缺失如何损害 TCR 驱动的激活,从而损害抗肿瘤效应反应,这无异于让 CD8 + T 细胞的脚离开油门。

更新日期:2020-10-13
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