Abstract

Four new triterpene glucosides (1–4) were isolated from the 90% ethanol extract of Salacia cochinchinensis, together with five known compounds (5–9). The structures of the new compounds were elucidated by comprehensive spectroscopic analysis including HRESIMS, IR, 1 D and 2 D NMR analysis. All isolates were assayed for their α-glucosidase inhibitory activity. Compound 9 showed remarkable α-glucosidase inhibitory activity with an IC₅₀ value of 0.31 μM, and the triterpene glycosides (1–5) exhibited moderate α-glucosidase inhibitory activity.

中文翻译：

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五层龙的四种新三萜苷

摘要

从五层龙的 90% 乙醇提取物中分离出四种新的三萜糖苷 ( 1-4 ) ，以及五种已知化合物 ( 5-9 )。通过包括 HRESIMS、IR、1D 和 2D NMR 分析在内的综合光谱分析阐明了新化合物的结构。测定所有分离物的α-葡糖苷酶抑制活性。化合物9表现出显着的α-葡萄糖苷酶抑制活性，IC ₅₀值为0.31 μM，三萜糖苷（1-5）表现出中等的α-葡萄糖苷酶抑制活性。