Silver nanoparticle in biosensor and bioimaging: Clinical perspectives,Biotechnology and Applied Biochemistry

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Silver nanoparticle in biosensor and bioimaging: Clinical perspectives
Biotechnology and Applied Biochemistry ( IF 3.2 ) Pub Date : 2020-10-11 , DOI: 10.1002/bab.2045
Peng Tan ₁ , HeSheng Li ₂ , Jian Wang ₃ , Subash C B Gopinath _{4,

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Affiliation

Recent developments in nanotechnology promoted the production of nanomaterials with various shapes and sizes by utilizing interdisciplinary researches of biology, chemistry, and material science toward the clinical perspectives. In particular, gold and silver (Ag) are noble metals that exhibit tunable and unique plasmonic properties for the downstream applications. Ag exhibits higher thermal and electrical conductivities, and more efficient in the electron transfer than gold with sharper extinction bands. In addition, modified Ag nanoparticle is more stable in water and air. With all these above features, Ag is an attractive tool in various fields, including diagnosis, drug delivery, environmental, electronics, and as antimicrobial agent. In particular, applications of Ag nanoparticle in the fields of biosensor and imaging are prominent in recent days. Enhancing the specific detection of clinical markers with Ag nanoparticle has been proved by several studies. This review discussed the constructive application of Ag nanoparticle in biosensor and bioimaging for the detection of small molecule to larger whole cell in the perspectives of diagnosing diseases.

中文翻译：

生物传感器和生物成像中的银纳米颗粒：临床观点

纳米技术的最新发展通过利用生物学、化学和材料科学的跨学科研究走向临床，促进了各种形状和尺寸的纳米材料的生产。特别是，金和银 (Ag) 是贵金属，在下游应用中表现出可调谐和独特的等离子体特性。Ag 表现出更高的导热性和导电性，并且在电子转移中比具有更锐利的消光带的金更有效。此外，改性银纳米粒子在水和空气中更稳定。凭借上述所有特性，Ag 在诊断、药物输送、环境、电子和抗菌剂等各个领域都是一种有吸引力的工具。特别是，近年来，Ag纳米粒子在生物传感器和成像领域的应用十分突出。几项研究已经证明，使用 Ag 纳米颗粒可以增强对临床标志物的特异性检测。本综述从诊断疾病的角度讨论了 Ag 纳米粒子在生物传感器和生物成像中的建设性应用，用于检测从小分子到更大的全细胞。

更新日期：2020-10-11

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