Notoedric mange, caused by sarcoptiform Notoedres mites, an obligately parasite, causes potentially fatal dermatitis along with secondary systemic infections in small mammals, felids as well as humans. In the present case study, we describe clinical diagnosis and therapeutic management of notoedric mange with ivermectin in rabbits. Two New Zealand White rabbits (Oryctolagus cuniculus) naturally infested with notoedric mange reported with history of varied clinical signs like anorexia, patchy alopecia, intense pruritus, erythema and dry scabs. Several whitish crust-like lesions were observed on ears, nose, face, forelimbs and hindlimbs. Confirmatory diagnosis of Notoedres cati var cuniculi was done by skin scraping from supported by clinical signs and hematological alterations. Both the animals were successfully treated with Ivermectin, a broad spectrum anti-parasitic agent. Both rabbits showed recovery by the end of third week of treatment and it was subsequently confirmed by absence of mites in two consecutive skin scrapings examination at weekly interval. The mite, Notoedres cati is considered as a serious pest of rabbits with ivermectin as still effective drug in treating the clinical cases. Stringent diagnostic strategies need to be prepared for regular screening and control of notoedric infestations in laboratory and pet rabbits.

中文翻译：

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用伊维菌素成功治疗兔子的 Notoedric 疥癣

Notoedric mange 由肉蚧螨（一种专性寄生虫）引起，在小型哺乳动物、猫科动物和人类中引起潜在致命的皮炎和继发性全身感染。在本案例研究中，我们描述了兔用伊维菌素对三香癣菌的临床诊断和治疗管理。两只新西兰白兔 (Oryctolagus cuniculus) 自然感染了雌性疥癣，据报道它们有多种临床症状，如厌食、斑片状脱发、剧烈瘙痒、红斑和干痂。在耳朵、鼻子、面部、前肢和后肢上观察到几个白色的痂状病变。Notoedres cati var cuniculi 的确诊是通过皮肤刮除得到临床症状和血液学改变的支持。两只动物都用伊维菌素成功治疗，一种广谱抗寄生虫药。两只兔子在治疗的第三周结束时都表现出恢复，随后在每周间隔的两次连续皮肤刮屑检查中证实没有螨虫。螨，Notoedres cati被认为是家兔的严重害虫，伊维菌素仍然是治疗临床病例的有效药物。需要准备严格的诊断策略，以定期筛查和控制实验室兔和宠物兔的雌雄同体感染。伊维菌素被认为是家兔的严重害虫，伊维菌素仍然是治疗临床病例的有效药物。需要准备严格的诊断策略，以定期筛查和控制实验室兔和宠物兔的雌雄同体感染。伊维菌素被认为是家兔的严重害虫，伊维菌素仍然是治疗临床病例的有效药物。需要准备严格的诊断策略，以定期筛查和控制实验室兔和宠物兔的雌雄同体感染。