The development of hardware for neural interfacing remains a technical challenge. We introduce a flexible, transversal intraneural tungsten:titanium electrode array for acute studies. We characterize the electrochemical properties of this new combination of tungsten and titanium using cyclic voltammetry and electrochemical impedance spectroscopy. With an in-vivo rodent study, we show that the stimulation of peripheral nerves with this electrode array is possible and that more than half of the electrode contacts can yield a stimulation selectivity index of 0.75 or higher at low stimulation currents. This feasibility study paves the way for the development of future cost-effective and easy-to-fabricate neural interfacing electrodes for acute settings, which ultimately can inform the development of technologies that enable bi-directional communication with the human nervous system.

中文翻译：

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W：Ti柔性横向电极阵列用于周围神经刺激的可行性研究

用于神经接口的硬件的开发仍然是技术挑战。我们为急性研究引入了一种灵活的，横向神经内钨：钛电极阵列。我们使用循环伏安法和电化学阻抗谱表征了钨和钛这种新组合的电化学性质。带着体内啮齿动物研究表明，用这种电极阵列刺激周围神经是可能的，并且在低刺激电流下，超过一半的电极触点可以产生0.75或更高的刺激选择性指数。这项可行性研究为开发将来用于急性环境的具有成本效益且易于制造的神经接口电极铺平了道路，这最终可以为能够与人类神经系统进行双向通信的技术的发展提供信息。