Objective. This paper was aimed at investigating the effects of bronchoalveolar lavage (BAL) with ambroxol hydrochloride (AH) on treating pulmonary infection and on serum proinflammatory cytokines and oxidative stress responses in patients with cerebral infarction (CI). Methods. One hundred and two patients with cerebral infarction complicated with pulmonary infection (CIPI) who were treated in our hospital were enrolled as research objects, divided into an observation group (52 cases; AH combined with BAL) and a control group (50 cases; single AH) based on therapeutic schemes. They were compared in terms of the therapeutic effect and pre- and posttreatment serum inflammatory cytokines, pulmonary function, and serum indices of oxidative stress. Their adverse reactions during treatment were also recorded and compared. Results. The therapeutic effect in the observation group was remarkably better than that in the control group (). After treatment, the serum inflammatory cytokines, pulmonary function, and serum indices of oxidative stress were remarkably improved in the two groups (), but the improvement was remarkably better in the observation group (). The differences were not significant in intratreatment adverse reactions between the two groups (). Conclusion. For CIPI patients, BAL with AH has a better therapeutic effect and higher safety and can control the patients’ systemic inflammatory responses and oxidative stress responses, so it is worthy of further promotion in clinical practice.

中文翻译：

---

盐酸氨溴索支气管肺泡灌洗治疗脑梗死患者肺部感染及对血清促炎细胞因子、MDA、SOD的影响

客观。本文旨在研究支气管肺泡灌洗液 (BAL) 与盐酸氨溴索 (AH) 对治疗肺部感染以及脑梗死 (CI) 患者血清促炎细胞因子和氧化应激反应的影响。方法. 以我院收治的脑梗死并发肺部感染（CIPI）患者102例为研究对象，分为观察组（52例；AH联合BAL）和对照组（50例；单次AH) 基于治疗方案。比较治疗效果及治疗前后血清炎性细胞因子、肺功能和血清氧化应激指标。他们在治疗过程中的不良反应也被记录和比较。结果。观察组治疗效果明显优于对照组（）。治疗后，两组血清炎性细胞因子、肺功能、血清氧化应激指标均有明显改善。），但观察组的改善明显更好（）。两组治疗期间不良反应差异无统计学意义（）。 结论。对于CIPI患者，BAL加AH治疗效果更好，安全性更高，可以控制患者全身炎症反应和氧化应激反应，值得在临床上进一步推广。