Near fibre electromyography (NFEMG) is the use of specifically high-pass filtered motor unit potential (MUPs) (i.e. near fibre MUPs (NFMs)) extracted from needle-detected EMG signals for the examination of changes in motor unit (MU) morphology and electrophysiology caused by neuromuscular disorders or ageing. The concepts of NFEMG, the parameters used, including NFM duration and dispersion, which relates to fibre diameter variability and/or endplate scatter, and a new measure of neuromuscular junction transmission (NMJ) instability, NFM segment jitter, and the methods for obtaining their values are explained. Evaluations using simulated needle-detected EMG data and exemplary human data are presented, described and discussed. The data presented demonstrate the ability of using NFEMG parameters to detect changes in MU fibre diameter variability, end plate scatter, and neuromuscular transmission time variability. These changes can be detected prior to alterations of MU size, numbers or muscle recruitment patterns.

中文翻译：

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近纤维肌电图

近纤维肌电图（NFEMG）是使用从针头检测到的EMG信号中提取的经过特殊高通滤波的电机单元电势（MUP）（即，近光纤MUP（NFM））来检查电机单元（MU）形态和由神经肌肉疾病或衰老引起的电生理。NFEMG的概念，所使用的参数（包括NFM持续时间和色散）与纤维直径可变性和/或终板散射有关，并且是神经肌肉接头传输（NMJ）不稳定性，NFM节段抖动的新度量及其获得方法值说明。提出，描述和讨论了使用模拟的针头检测到的EMG数据和示例性人类数据进行的评估。所提供的数据证明了使用NFEMG参数检测MU纤维直径变化的能力，终板散布，以及神经肌肉传递的时间变异性。这些变化可以在MU大小，数量或肌肉募集模式改变之前被检测到。