ABSTRACT

We have recently reported that transgenic mice overexpressing the HMGA1-pseudogene7 develop hematological neoplasia marked by monoclonal B-cell populations, and diagnosed as Diffuse Large B-cell Lymphoma. These findings prove the HMGA1-pseudogene7 oncogenic role in vivo.

中文翻译：

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HMGA1-pseudogene7 显示体内致癌活性

摘要

我们最近报道了过度表达HMGA1-pseudogene7 的转基因小鼠会出现以单克隆 B 细胞群为特征的血液肿瘤，并被诊断为弥漫性大 B 细胞淋巴瘤。这些发现证明了HMGA1-pseudogene7体内致癌作用。