Abstract

Synsepalum dulcifificum is an evergreen shrub native of tropical West Africa. It is very effective against a variety of diseases. However, the phytochemical investigation on this plant is limited till now. In our current study, seventeen compounds were isolated and identified from the ethyl acetate extract of the leaves. All of the compounds were obtained from S. dulcifificum for the first time. Compounds 4 and 9 were isolated from natural source for the second time. Moreover, the antioxidant activities of compounds 1, 4, 5, 9-11, and 15 were evaluated firstly. Compounds 6, 7, 13, and 14 exhibited significant antioxidant activity in DPPH and ABTS + assays, suggesting their potential application for an antioxidant drug.

摘要

Synsepalum dulcifificum是一种原产于热带西非的常绿灌木。它对多种疾病非常有效。然而，到目前为止，对该植物的植物化学研究是有限的。在我们目前的研究中，从叶子的乙酸乙酯提取物中分离并鉴定了 17 种化合物。所有化合物均为首次从S. dulcifificum中获得。化合物4和9为第二次从天然来源中分离得到。此外，化合物的抗氧化活性1，4，5，9 - 11，和15为首次评价。化合物6、7、13和14在 DPPH 和 ABTS + 测定中表现出显着的抗氧化活性，表明它们具有作为抗氧化药物的潜在应用。