Almost two decades after a worldwide call of Wirz‐Justice and collaborators published in Science for including light therapy (LT) in the therapeutic armamentarium of major depressive episodes (MDE), LT is still absent from international therapeutic guidelines. Psychiatrists’ resistance to non‐conventional therapeutics, although natural, usually results from lack of knowledge of mechanisms and response rates relative to reference drugs. A wealth of basic neuroscience and clinical studies has since then emerged, that now attest unequivocally to LT’s efficacy.

中文翻译：

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减轻抑郁症

在Wirz-Justice及其合作者在全球范围内呼吁将光疗（LT）纳入重度抑郁发作（MDE）的治疗设备中之后，近二十年来，国际治疗指南仍然没有LT。精神科医生对非常规疗法的抵抗力虽然很自然，但通常是由于相对于参比药物缺乏对机制和反应率的了解所致。从那时起，已经出现了大量的基础神经科学和临床研究，现在明确证明了LT的功效。