Objective The epidemiology of psychiatric symptoms among COVID-19 patients is poorly characterized. This paper seeks to identify the prevalence of anxiety, depression, and acute stress disorder among hospitalized patients with COVID-19. Methods Adult patients recently admitted to non-ICU medical ward settings with COVID-19 were eligible for enrollment. Enrolled patients were screened for depression, anxiety, and delirium. Subsequently, patients were followed by phone after two weeks and re-screened for depression, anxiety, and acute stress disorder symptoms. Subjects’ medical records were abstracted for clinical data. Results 58 subjects were enrolled of whom 44 completed the study. Initially, 36% of subjects had elevated anxiety symptoms and 29% elevated depression symptoms. At two-week follow-up, 9% had elevated anxiety symptoms, 20% elevated depression symptoms, and 25% mild-to-moderate acute stress disorder symptoms. Discharge to home was not associated with improvement in psychiatric symptoms. Conclusion A significant number of patients hospitalized with COVID-19 experience symptoms of depression and anxiety. While anxiety improves following index admission, depression remains fairly stable. Furthermore, a significant minority of patients experience acute stress disorder symptoms, though these are largely mild-to-moderate.

中文翻译：

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COVID-19 住院患者的抑郁、焦虑和急性应激障碍：一项前瞻性队列研究

目的 COVID-19 患者精神症状的流行病学特征很差。本文旨在确定住院 COVID-19 患者中焦虑、抑郁和急性应激障碍的患病率。方法 近期因 COVID-19 入住非 ICU 病房的成年患者有资格入组。入组的患者接受了抑郁、焦虑和谵妄的筛查。随后，患者在两周后通过电话进行随访，并重新筛查抑郁、焦虑和急性应激障碍症状。受试者的医疗记录被提取用于临床数据。结果 58 名受试者入选，其中 44 名完成了研究。最初，36% 的受试者焦虑症状升高，29% 的抑郁症状升高。在两周的随访中，9% 的人焦虑症状加重，20% 的抑郁症状升高，25% 轻度至中度急性应激障碍症状。出院回家与精神症状的改善无关。结论 大量 COVID-19 住院患者出现抑郁和焦虑症状。虽然焦虑在指数入院后有所改善，但抑郁症仍然相当稳定。此外，相当一部分患者会出现急性应激障碍症状，尽管这些症状主要是轻度至中度。抑郁症仍然相当稳定。此外，相当一部分患者会出现急性应激障碍症状，尽管这些症状主要是轻度至中度。抑郁症还是比较稳定的。此外，相当一部分患者会出现急性应激障碍症状，尽管这些症状主要是轻度至中度。