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Immunolocalization of androgen and vitamin D receptors in the epididymis of mature ram (Ovis aries)
Saudi Journal of Biological Sciences ( IF 4.4 ) Pub Date : 2020-10-09 , DOI: 10.1016/j.sjbs.2020.09.051
Yasmine Asaad Mansour , El-Sayed M.M. Mosallam , Shaymaa Hussein , Ebtihal M.M. Elleithy , Ihab M. Moussa , Ayman S. Mubarak , Turki M. Dawoud , Roua A. Alsubki , Jwaher H. Alhaji , Hassan A. Hemeg , Gehad A.H. EL-Bargeesy

This study illustrated the immunohistochemical distribution of androgen and vitamin D receptors of epididymis in 20 sexually mature ram (Rahmani breed) with average age ranged from (2_4) years and average weight ranged from (50_65kg). Androgen receptor was localized in the cytoplasm of both ciliated and non ciliated cells of efferent ductules, besides the principal cells via the entire epididymal duct. The principal cells of both corpus and proximal cauda epididymis showed the highest immunoreactivity to androgen receptors. Furthermore, vitamin D receptor was localized in the cytoplasm of all epithelium of the efferent ductules besides principal cells of all epididymal regions, however the immunoreaction was significantly higher in the efferent ductules, distal caput and distal cauda epididymis. In conclusion, these results suggest that the function of ram epididymis is regulated by both androgen and Vitamin D.



中文翻译:

在成熟羊的附睾雄激素和维生素d受体的免疫组化(绵羊白羊

这项研究说明了在20个性成熟的公羊(Rahmani品种)中附睾的雄激素和维生素D受体的免疫组织化学分布,其平均年龄为(2 _ 4)岁,平均体重为(50 _)。65公斤)。雄激素受体定位在传出导管的纤毛和非纤毛细胞的胞质中,除了主要细胞通过整个附睾管。体和附睾近端附睾的主要细胞对雄激素受体表现出最高的免疫反应性。此外,维生素D受体除了位于所有附睾区域的主要细胞外,还位于传出小管的所有上皮细胞质中,但是在传出小管,远端小管和远端马尾附睾中的免疫反应明显更高。总之,这些结果表明,ram附睾的功能受雄激素和维生素D的调节。

更新日期:2020-10-09
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