The present study evaluated the fabrication of methyl methacrylate-based polymer nanoparticles by miniemulsion and combined miniemulsion/emulsion polymerization using an atomization apparatus with two-fluid nozzle. In both reactions, the effects of the operational conditions were investigated on the morphology and particle size distribution of polymer particles. After multivariate analysis, it was observed that the size of the poly(methyl methacrylate) particles is a function of gas pressure in the experiments stabillized by sodium lauryl sulfate (SLS), but this did not occur in reactions stabillized by inorganic and polymeric stabilizers. The use of inorganic stabilizer made possible the fabrication of polymer particles smaller than 300 nm. In combined miniemulsion/emulsion polymerization with SLS, high concentrations of surfactant (> 0.4% w/w) and intermittent monomer feeding enabled not only an increase of the solid concentrations, but also a reduction of particle size. In addition, styrene-methyl methacrylate nanoparticles were successfully obtained (< 30 nm), according to dynamic light scattering and transmission electron microscopic analyses.

中文翻译：

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使用雾化装置通过细乳液和组合细乳液/乳液聚合制备甲基丙烯酸甲酯基聚合物颗粒

本研究评估了使用具有双流体喷嘴的雾化装置通过细乳液和组合细乳液/乳液聚合制备甲基丙烯酸甲酯基聚合物纳米粒子。在这两个反应中，研究了操作条件对聚合物颗粒的形态和粒度分布的影响。在多变量分析后，观察到聚甲基丙烯酸甲酯颗粒的大小是由十二烷基硫酸钠 (SLS) 稳定的实验中气压的函数，但在无机和聚合物稳定剂稳定的反应中不会发生这种情况。无机稳定剂的使用使得制造小于 300 nm 的聚合物颗粒成为可能。在与 SLS 组合的细乳液/乳液聚合中，高浓度的表面活性剂 (> 0. 4% w/w) 和间歇性单体进料不仅可以增加固体浓度，还可以减小颗粒尺寸。此外，根据动态光散射和透射电子显微镜分析，成功获得了苯乙烯-甲基丙烯酸甲酯纳米颗粒（< 30 nm）。