In response to the increasing number and breadth of innovation studies on the pharmaceutical industry, we mapped the literature to show the trends in recent research and to indicate areas for further research. In the first phase, we analyzed articles on the pharmaceutical industry published in innovation journals. We used these articles’ textual and citation data and applied hybrid cluster analysis. Three main clusters were produced based on the level of analysis innovation scholars had used to investigate the industry: macro, meso and micro. We describe the research topics within these clusters and show that, overall, innovation scholars increasingly focus on the meso-level, analyzing the relationships across different firms. This shift in interest toward the collaborative nature of drug discovery and development was also apparent in macro- and micro-level studies. To explore how this literature is used by scientists in the industry, our second phase involved analysis of the citing articles published in pharmaceutical journals. Using our findings, we propose research areas that can be further explored in order to create an engaged and better-integrated literature on pharmaceutical innovation.

中文翻译：

---

药物研发创新：绘制研究图景

为了应对制药行业创新研究的数量和广度不断增加，我们绘制了文献以显示近期研究的趋势并指出需要进一步研究的领域。在第一阶段，我们分析了在创新期刊上发表的关于制药行业的文章。我们使用这些文章的文本和引文数据并应用混合聚类分析。根据创新学者用来调查行业的分析水平，产生了三个主要集群：宏观、中观和微观。我们描述了这些集群中的研究主题，并表明，总的来说，创新学者越来越关注中观层面，分析不同公司之间的关系。这种对药物发现和开发协作性质的兴趣转变在宏观和微观研究中也很明显。为了探索行业科学家如何使用这些文献，我们的第二阶段涉及对发表在制药期刊上的施引文章的分析。使用我们的发现，我们提出了可以进一步探索的研究领域，以创建关于药物创新的参与性和更好整合的文献。