A retrospective, single-center analysis of 14 cases of Candida endocarditis (from 355 candidemia cases during the years 2012–2019) revealed a high in-hospital mortality (57.1%), a high proportion of healthcare-associated infections (13/14) and a high treatment preference for echinocandins. Transthoracic echocardiography and ¹⁸F-FDG PET/CT had a sensitivity of 54.5% and 57.1%, respectively. Patients were older than previously described and most patients with Candida endocarditis had persistent candidemia for ≥ 3 days despite antifungal therapy.

中文翻译：

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念珠菌血症患者念珠菌心内膜炎：14例单中心经验

对 14 例念珠菌心内膜炎（2012 年至 2019 年期间 355 例念珠菌血症）进行的回顾性单中心分析显示，院内死亡率高（57.1%），医疗相关感染比例高（13/14）以及对棘白菌素的高度治疗偏好。经胸超声心动图和¹⁸ F-FDG PET/CT 的敏感性分别为 54.5% 和 57.1%。患者比之前描述的年龄大，大多数念珠菌心内膜炎患者尽管接受了抗真菌治疗，但仍有持续 ≥ 3 天的念珠菌血症。